Joschka T. Müller is a licensed pharmacist in Germany since 2022 and a fourth-year PhD candidate at LMU Munich. His research in Prof. Dr. Olivia Merkel’s lab focuses on developing siRNA polyplex therapies targeting human betacoronaviruses, addressing challenges in pulmonary delivery. To improve translational relevance, he uses advanced 3D models like Air-Liquid Interface (ALI) cultures and Precision-Cut Lung Slices (PCLS), enhancing predictive accuracy while adhering to 3R principles for ethical preclinical research.